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Streptomycin

Date: 2016-05-20 14:28   Writer: admin
Streptomycin is a water-soluble aminoglycoside antibiotican antibiotic that used to treat bacterial diseases in cattle, pigs, sheep and poultry. It kills or inhibits sensitive bacteria by stopping protein synthesis. The chemical   name of streptomycin is O-2-DEOXY- (METHYLAMINO)-alpha – L- GLUCOPYRANOSYL-(1–>2)-O-5-DEOXY-3C-FORMYL-alpha-L-LYXOFURANOSYL-(1–>4)-N,N’-bis(AMINOIMINOMETHYL)-D-STREPTAMINE(JECFA. 2002). WHO has been set MRLs for streptomycin(expressed as the sum of the concentrations of dihydrostreptomycin and streptomycin) at 0.2mg/kg in milk. The MRLs  recommended at  the  fifty-second meeting: 600 μg/kg for  muscle, liver  and fat of  cattle, pigs, sheep and chickens; 1000 μg/kg for kidney from cattle, pigs, sheep and chickens.The European commission and Codex Alimentarius MRLs have been set at 200ug/kg in both bovine and ovine milk.